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KMID : 1145720200080020233
Korean Herbal Medicine Informatics
2020 Volume.8 No. 2 p.233 ~ p.242
Comparative Study on the Component Pattern of Scutellaria baicalensis roots distributed in Korea using HPLC
Kim Hyo-Seon

Seo Young-Hye
Yang Sun-Gyu
Seo Chang-Seob
Lee A-Yeong
Ryu Seung-Mok
Choi Go-Ya
Moon Byeong-Cheol
Lee Jun
Abstract
This study compares and analyzes the difference in components between the two types of Scutellaria baicalensis roots according to morphological discrimination. The roots of S. baicalensis are divided into two types, Jo-geum and Go-geum, according to the harvest time and shape, and these have been used for different therapeutic purposes. But currently, comparative studies on the chemical constituents and efficacy of them are insufficient. In this study, a total of 14 samples of S. baicalensis roots, distributed in Korea, were collected and divided into two types (Jo-geum and Go-geum) through morphological discrimination. Their main four components, baicalin (1), wogonoside (2), baicalein (3), and wogonin (4), were identified and analyzed using high-performance liquid chromatography with a photodiode array detector. As a result, the signal of wogonin (4) showed a significant difference between the two types. A relatively higher level of signals was detected in the Go-geum samples regardless of the origin. In addition, these component patterns were consistent with the morphological discrimination results.
KEYWORD
Scutellaria baicalensis, Labiatae, Jo-geum, Go-geum, Wogonin
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