KMID : 1145720200080020233
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Korean Herbal Medicine Informatics 2020 Volume.8 No. 2 p.233 ~ p.242
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Comparative Study on the Component Pattern of Scutellaria baicalensis roots distributed in Korea using HPLC
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Kim Hyo-Seon
Seo Young-Hye Yang Sun-Gyu Seo Chang-Seob Lee A-Yeong Ryu Seung-Mok Choi Go-Ya Moon Byeong-Cheol Lee Jun
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Abstract
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This study compares and analyzes the difference in components between the two types of Scutellaria baicalensis roots according to morphological discrimination. The roots of S. baicalensis are divided into two types, Jo-geum and Go-geum, according to the harvest time and shape, and these have been used for different therapeutic purposes. But currently, comparative studies on the chemical constituents and efficacy of them are insufficient. In this study, a total of 14 samples of S. baicalensis roots, distributed in Korea, were collected and divided into two types (Jo-geum and Go-geum) through morphological discrimination. Their main four components, baicalin (1), wogonoside (2), baicalein (3), and wogonin (4), were identified and analyzed using high-performance liquid chromatography with a photodiode array detector. As a result, the signal of wogonin (4) showed a significant difference between the two types. A relatively higher level of signals was detected in the Go-geum samples regardless of the origin. In addition, these component patterns were consistent with the morphological discrimination results.
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KEYWORD
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Scutellaria baicalensis, Labiatae, Jo-geum, Go-geum, Wogonin
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